Preface, xvAcknowledgements, xviiAbout the authors, xixAbout the companion website, xxi1 Lipids: definitions, naming, methods and a guide to the contents of this book, 11.1 Introduction, 11.2 Definitions, 11.3 Structural chemistry and nomenclature, 11.4 Lipidomics, 41.5 A guide to the contents of this book, 8Key points, 11Further reading, 122 Important biological lipids and their structures, 132.1 Structure and properties of fatty acids, 132.2 Storage lipids triacylglycerols and wax esters, 202.3 Membrane lipids, 26Key points, 42Further reading, 423 Fatty acid metabolism, 443.1 The biosynthesis of fatty acids, 443.2 Degradation of fatty acids, 853.3 Chemical peroxidation is an important reaction particularly of polyunsaturated fatty acids, 953.4 Peroxidation catalysed by lipoxygenase enzymes, 963.5 Essential fatty acids and the biosynthesis of eicosanoids, 100Key points, 120Further reading, 1214 The metabolism of complex lipids, 1244.1 The biosynthesis of triacylglycerols, 1244.2 The catabolism of acylglycerols, 1334.3 The integration and control of animal acylglycerol metabolism, 1364.4 Wax esters, 1434.5 Phosphoglyceride biosynthesis, 1464.6 Degradation of phospholipids, 1574.7 Metabolism of glycosylglycerides, 1634.8 Metabolism of sphingolipids, 1654.9 Cholesterol biosynthesis, 173Key points, 182Further reading, 1835 Roles of lipids in cellular structures, 1875.1 Lipid assemblies, 1875.2 Role of lipids in cellular evolution, 1935.3 Membrane structure, 2015.4 Membrane function, 2065.5 Intracellular lipid droplets, 2155.6 Extracellular lipid assemblies, 222Key points, 226Further reading, 2276 Dietary lipids and their biological roles, 2296.1 Lipids in food, 2296.2 Roles of dietary lipids, 233Key points, 251Further reading, 2517 Lipid assimilation and transport, 2537.1 Lipid digestion and absorption, 2537.2 Transport of lipids in the blood: plasma lipoproteins, 2617.3 The coordination of lipid metabolism in the body, 275Key points, 284Further reading, 2858 Lipids in transmembrane signalling and cell regulation, 2878.1 Phosphoinositides have diverse roles in cell signalling and cell compartmentation, 2888.2 Endocannabinoid signalling, 2998.3 Lysophosphatidate and sphingosine 1-phosphate in the circulation regulate cell motility and proliferation, 2998.4 Signalling by phospholipase D, at least partly through phosphatidate, 3008.5 Ceramide regulates apoptosis and other cell responses, 301Key points, 302Further reading, 3039 The storage of triacylglycerols in animals and plants, 3049.1 White adipose tissue depots and triacylglycerol storage in animals, 3049.2 Brown adipose tissue and its role in thermogenesis, 3109.3 Lipid storage in plants, 313Key points, 314Further reading, 31510 Lipids in health and disease, 31710.1 Inborn errors of lipid metabolism, 31710.2 Lipids and cancer, 32310.3 Lipids and immune function, 32810.4 Effects of too much or too little adipose tissue: obesity and lipodystrophies, 33810.5 Disorders of lipoprotein metabolism, 349Key points, 364Further reading, 36511 Lipid technology and biotechnology, 36711.1 Introduction, 36711.2 Lipid technologies: from surfactants to biofuels, 36711.3 Lipids in foods, 37511.4 Modifiying lipids in foods, 37911.5 Modifying lipids in nonedible products, 38311.6 Lipids and genetically modified organisms, 385Key points, 390Further reading, 390Index and list of abbreviations, 391